San Isidro Vacation Packages
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Your San Isidro Vacation
Say goodbye to the hassle of planning and hello to a San Isidro vacation package. With the finer details organized before you take off, you can focus on discovering every inch of this city, starting with Cartagena Walled City, which is great for views, dining and bars and pubs. If a sightseeing tour is part of the program during your trip to San Isidro, stop by leading attractions like San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium. Whoever you're heading away with and whatever you want to spend, your ultimate San Isidro vacation is just a few clicks away with Expedia.
Top Holiday Package Deals in San Isidro
Price found within the past 48 hours. Click for updated prices.
Hotel Quadrifolio
Cartagena Walled City
CA $1,564
per person
Dec 6 - Dec 10
found 17 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Cartagena (CTG)
10/10 Exceptional! (170 reviews)
Una experiencia increíble de principio a fin. No tenemos palabras para agradecer a Jannia y a todo el equipo de Hotel Quadrifolio. Desde antes de llegar estuvieron pendientes de cada detalle y nos ayudaron a organizar prácticamente todo el viaje. Siempre fueron súper atentos, amables y dispuestos a ayudarnos con cualquier cosa que necesitáramos. El hotel es hermoso, la habitación muy cómoda, los desayunos increíbles y la ubicación no podría ser mejor. Además, en todo momento nos sentimos muy cómodos y seguros. Pero lo que realmente hizo especial nuestra estadía fue la atención del equipo. Jannia y todo el staff hicieron que nuestro viaje a Cartagena y el cumpleaños de mi esposa fueran todavía más especiales. Gracias de corazón por todo. Sin duda volveríamos a hospedarnos en Quadrifolio y lo recomendamos 100%.
Reviewed on Oct 19, 2026
Casa Bali Castillo View Private Pool & R
Pie del Cerro
CA $2,693
per person
Dec 11 - Dec 18
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Cartagena (CTG)
10/10 Exceptional! (1 review)
Excelente ubicación, buenas instalaciones, en la recepción tanto Omar como la recepcionista fueron muy amables en todo momento.
Reviewed on Feb 17, 2026
Aura Hotel Barú
CA $1,569
per person
Jan 13 - Jan 17
found 16 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Cartagena (CTG)
8.2/10 Very good! (138 reviews)
Aura far exceeded all expectations!!! The place is so spectacularly beautiful and the staff is beyond professional, helpful, friendly and fun. To anyone planning a trip to Cartagena, I HIGHLY recommend taking a few days to relax at this very special place.
Reviewed on Sep 14, 2026
Where to stay in San Isidro
Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro
Cartagena Walled City
3 out of top 10 points of interest in this area
Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.
Bocagrande
1 out of top 10 points of interest in this area
Boasting the city's most prominent hotels, this upscale area offers shopping at Plaza Bocagrande and Nao Mall, and is close to the popular Ciudad Amurallada. Enjoy various dining options and easy access to the Transcaribe station.
Getsemani
Travelers come to Getsemani for its abundant dining options, and you can see top attractions like Plaza de la Trinidad and Los Pegasos Dock while you're in town.
Cartagena Centro
Unique features of Cartagena Centro include the museums and historic sites. Make a stop by Plaza Santo Domingo or Bolivar Square while you're exploring the area.
San Diego
San Diego is known for its ample dining options, and you can make a stop by House of Gabriel Garcia Marquez and Las Bovedas while in the area.
San Isidro Hotel Deals
OZ Hotel Collection
6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
CA $141
CA $141 total
Oct 26 - Oct 27
Sofitel Barú Cartagena
KM 7 Sector, Porto Nao Cartagena Bolívar
Fully refundableReserve now, pay when you stay
CA $460
CA $460 total
Nov 8 - Nov 9
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
Anillo Vial, Km 12, between Manzanillo Cartagena Bolivar
Fully refundableReserve now, pay when you stay
CA $406
CA $406 total
Nov 10 - Nov 11
8.2/10 Very good! (1,001 reviews)
"Clean room, excellent staff, and excellent... I mean EXCELLENT drinks (haha)! Shoutout to Leidy and Diego."
Reviewed on Oct 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a San Isidro vacation package cost?
Our San Isidro vacation packages, which begin at just CA $1,564, are the perfect way to save big. Select your favorite hotels, flights and more to create a personalized escape.
How do I get a cheap travel package to San Isidro?
Booking a flight and hotel together with Expedia won't just save precious time — it'll save you a pretty penny too. A San Isidro vacation package makes it a cinch to organize your ideal trip. With more than 550 airlines throughout the world to select from, finding flights that fit your busy schedule will be no sweat. Not only that, we've got over 1,000,000 hotels globally to pick from. Now that's what you call choice. No matter who you are, Expedia will help show you the world.
Where should I stay in San Isidro?
Most visitors who travel to San Isidro include San Felipe de Barajas Castle and San Pedro Claver Church and Convent on their bucket lists. Why not select a hotel right near these main attractions?
How far in advance should I book my San Isidro vacation?
Be rewarded with the widest variety at the lowest prices by booking your trip to San Isidro early. Air carriers typically release flight tickets anywhere up to 12 months in advance, so start locking things in as soon as you can. That being said, Expedia is constantly working to give you the best deals around, so it's always a good time to book your dream vacation!
What does an Expedia San Isidro travel package include?
It comes down to what sort of escape you have in the works. San Isidro vacation deals can include car rentals, flights and hotels. You can mix and match to find the bundle that suits your style and budget. You can also add on activities and experiences after you've booked to land even bigger discounts.
What should I know before booking a San Isidro travel package?
A travel package can be tailored to your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Hotels, rental cars and flights — come up with a combination that suits your plans.
Can I choose my airline with a San Isidro Expedia vacation package?
With a vacation package, you're the boss. Whether you're hoping to fly to San Isidro in coach or first class, simply select from the available airline options. Expedia has access to more than 550 airline partners throughout the world.
If I'm not able to travel, can I cancel my San Isidro vacation package?
Whether it's your hotel or flight, yes, you can cancel or amend it. Locked in your San Isidro vacation package in the last 24 hours? You may be able to make changes or cancellations at no cost. For older bookings, you may be charged a fee by your airline, hotel or car rental company. For more details, take a look at our Customer Service Portal. We'll help you each step of the way.
Things to do
Cartagena 5 Island Hop Tour: Lunch, Snorkel, Beach Clubs, & More
CA $99
per adult
84% of travellers recommend
Full-Day Volcano of Totumo With Lunch, 5 pools and prívate Bach
CA $85
per adult
80% of travellers recommend
Cartagena: Rosario Islands Excursion with Snorkeling and Playa Blanca in Barú
CA $106
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.